Guide to Advair Intake Instructions

Advair intake instructions are simple but need to be followed to be effective.  Flowing Advair intake instructions will avoid unnecessary complications and side effects.  You are to follow the Advair intake instructions provided by the doctor first before you follow any other dosing procedures you might find elsewhere.  This is a measure necessary to ensure that you are using the medication in a way that is tailored to your needs and leaves you at the smallest risk of dangerous interactions due to unanticipated reactions to the drug.  Introductory and initial Advair intake instructions generally should be followed until you are sure how you will react when taking Advair, including side effects, fatigue and other possible impairments.

What are the typical Advair intake instructions?

Again, you need to follow the instructions provided by the pharmacy or doctor, before you follow the manufacturer’s Advair intake instructions.  Note that while there are different concentrations of Advair Diskus and Advair HFA the instructions for dosage are largely the same.  Both forms must be taken twice daily and spaced 12 hours apart.  The doses must remain consistent in order for the medication to be effective at managing asthma symptoms.  All directions state that the patient must rinse and spit after taking an Advair dose.  This prevents the formation of Thrush, which is a type of yeast infection in the mouth.

What happens if I miss a dose?

If you miss a dose, you generally should not make it up when you remember it, unless you are reasonably spaced from the next scheduled dose.  If is generally best to miss the dose rather than make it up as you will want to avoid overdosing on the medication.  Overdoses are marked by problems breathing and dizziness.

Advair intake instructions for the HFA inhaler

The HFA inhaler delivers both the corticosteroid and airway relaxant in aerosol form, which is preferred by those that are irritated by the powder shot by the Advair discuss.  The inhaler needs to be primed and the typical inhaler comes with 124 doses preloaded.  4 doses are expelled, as per Advair intake instructions, when priming the inhaler for use.  The remaining 120 is the appropriate number of doses.  This should last a patient roughly two months in a typical dosing schedule.

Advair intake instructions to clear devices

You must follow the directions to clean all devices.  This ensures that the Advair can flow freely and that harmful residue is removed before it becomes a toxic concentration or increases the chance of secondary infections in the mouth.  Swabbing and proper care is necessary to keep the inhaler in working order until a new one is issued.  Also, note that the old inhalers must be disposed of once all the doses have counted down.  There might be medication left, but there are no guarantees as to the safety and suitability of this medication beyond that point, especially in the right measured dose.

 

What are the differences between Advair HFA vs. Advair Diskus?

There are two major differences between Advair HFA vs. Advair Diskus.  In an Advair HFA vs. Advair Diskus comparison, HFA contains salmeterol.  This is a beta agonist, which opens the airways and helps patients that struggle with breathing.  This is consistently 21 mcg concentration per inhaler regardless of the version of the Advair HFA provided to the patient.  The other active ingredient, which is common to both Advair HFA vs. Advair Diskus is fluticasone and the dosage will depend on the severity of the condition of the patient.

How is the delivery system different for the Advair HFA vs. Advair Diskus?

The Diskus gets its name from its unique shape and delivery system, using a compressed gas to shoot the corticosteroid into the airways.  It still must be cleaned regularly to ensure it is effective and residue is not ingested during the dosing. Advair HFA is delivered through a conventional inhaler.  This inhaler has to be primed and includes a counter that shows how many proper doses are left.  Instructions state to replace this inhaler once there are twenty doses to go and doses after the counter runs out cannot be trusted to be the reliable measured dose.

What are some similarities of Advair HFA vs. Advair Diskus?

Advair HFA vs. Advair Diskus are essentially the same medication, with the addition of the salmeterol in Advair HFA to treat more severe lung disorders and trouble breathing.  Both medications need to be taken twice a day under a normal dose, twelve hours apart.  In addition, the inhaler has to be cleaned at least once a week.  a danger with both medications is the potential for infection and thrush in the mouth, so both instruct those using the inhaler to rise and spit after every dose as well as clear the inhaler of residue every week.  Follow the manufacturer’s instructions to clean the inhaler or Diskus weekly and avoid secondary infection or dosing improperly.

The doses must be taken consistently to be effective.  With that in mind, you will take this medication until instructed otherwise by the medical professional monitoring your asthma.

Differences in concentration for Advair HFA vs. Advair Diskus

Advair HFA comes in three forms, with differing concentrations of the corticosteroid, in micrograms.  These concentrations are 45, 115 and 230 and each inhaler is measured to have 120 doses.  The counter will read 124 as you are expected to depress the inhaler four times to prime it for use.  You will also have to prime the inhaler if several weeks have passed since the last dose, though you have to take Advair every day unless the doctor notes otherwise.

 

Dangerous Drug Facts: Symbyax

 

 

Common Uses of Symbyax

 

 

Symbyax’s (Olazapine and Fluoxetine HCI Capsules) uses include treatment of treatment-resistant (TRD) and bipolar I depression in adults.  Symbyax was first developed to treat bipolar I depression, and the Food and Drug Administration (FDA) later approved the medication for treatment with TRD.

 

 

Treatment-resistant depression is defined as a major depressive disorder in adults who do not respond to 2 or more separate trials of different antidepressants in significant doses and duration.  Symbyax’s release on the market has helped numerous individuals, but the drug has also shown serious and sometimes fatal side effects. 

 

 

If you are experiencing any of the side effects listed within this article associated with Symbyax’s use, you need to tell a family member and contact your doctor right away.  

 

 

Dangerous Side Effects of Symbyax

 

 

Antidepressants like Sym. have been known to increase thoughts of suicide and similar behavior in children, teens, and young adults.  Sym is prescribed to adults, but if you or anyone you know show signs of new or worsening depression symptoms, unusual changes in behavior, or thoughts or suicide, you need to contact a doctor immediately.  

 

 

The symptoms associated with Symbyax’s use may appear more frequently during the first couple of months of treatment or if the dose amount is changed by a physician.  Sym. is not prescribed to child or adolescents because of its high correlation with increased suicidal thoughts, and the medication is not prescribed to elderly patients with dementia-related psychosis.  

 

 

What should I discuss with my doctor before taking Symbyax?

 

 

Your doctor will review your medical history and past medications when thinking about prescribing Sym.  You should never take Symbyax if you’ve taken a Monoamine Oxidase Inhibitor (MAOI) in the last two weeks, and you should never take an MAOI within 5 weeks of stopping Sym.  The side effects associated with Symbyax’s use and a MAOI at the same time can be serious and deadly.  

 

 

Your doctor will not prescribe Sym. if you’ve already take Mellaril (thioridazine) or the antipsychotic medicine pimozide (Orap).  Additionally, your doctor will not prescribe Sym. if you take any olanzapines liked Zyprexa, Zyprexa Relprew, or Zyprexa Zydis or take any fluoxetine hydrochlorides like Prozac, Prozac Weekly, or Sarafem.  You should also discuss all other prescription and over-the-counter drugs (including herbs) you take while discussing Symbyax’s use with your doctor.  

 

 

Additionally, you’ll want to discuss any health concerns you’ve had in the past or may have in the future before taking Symbyax.  Your doctor may avoid prescribing Sym. if any of the following conditions apply: 

 

 

• Heart problems

 

• Seizures

 

• Diabetes or high blood sugar levels

 

• High cholesterol or triglyceride levels

 

• Liver problems

 

• Low or high blood pressure

 

 

• Strokes or “mini-strokes”

 

• bleeding problems 

 

• Alzheimer’s disease or family history

 

• Narrow-angle glaucoma

 

• Enlarged prostate 

 

• Bowel obstruction

 

• Breast cancer

 

• Plans to become pregnant or if you are already pregnant 

 

 

Common Side Effects Associated with Symbyax

 

 

Symbyax’s use can cause common side effects, and a doctor will only prescribe Sym. if they believe the positive benefits of the medication outweigh the negative effects.  A doctor will usually start a patient out with a small dose of Symbyax and gradually work them up to a normal dose of 3mg/25mg, 6mg/25 mg, 6mg/50mg, 12mg/25mg, or 12mg/50mg of olanzapine/fluoxetine.  

 

 

Side effects may increase or decrease depending on Symbax’s dose amount, and some common side effects associated with the drug include the following: 

 

 

• Tiredness 

 

• feeling weak

 

• increased appetite 

 

• sleep for long periods of time

 

• blurred vision

 

• Tremors or shakes

 

• Dry mouth

 

• swelling of the hands and feet

 

 

There are other side effects associated with Symbyax’s use, and you’ll want to read the information packet that comes along with your medication in order to identify related side effects in the future.  

 

 

Other Serious and Dangerous Side Effects While Using Symbyax

 

 

Symbyax’s use can cause other serious side effects apart from suicidal thoughts or actions.  Most people will show no side effects while taking Sym. but others may face any of the serious side effects: 

 

 

1. High Blood Sugar (hyperglycemia) – taking Sym. will usually increase everyone’s blood sugar a bit, but having a history of diabetes can pose a serious risk to your well-being, and common signs of high blood sugar include the following: 

 

 

• feeling abnormally thirsty

 

• need to urinate more than usual

 

• feeling very hungry

 

• feeling weak or tired

 

• feeling sick to the stomach

 

• Feeling confused

 

• Fruity smelling breath 

 

 

2. High Cholesterol and Triglycerides- Symbyax’s use can cause very high fat levels in the blood if the patient took olanzapine before they were 18

 

 

3. Increase Weight- Symbyax’s use will usually cause a person to gain some weight, and some individuals may gain more weight than others

 

 

4. Severe Allergic Reactions- Symbyax’s use can cause severe and life threatening allergic reactions, and you need to contact a doctor immediately if you experience hives or a rash, high fever and joint pain, swelling of the face, eyes, or mouth

 

 

5. Neuroleptic malignant syndrome- NMS is rare but can cause death if not treated, and you need to contact your doctor if you experience any high fever, excessive sweating, rigid muscles, confusion, or changes in breathing, heartbeat, or blood pressure while taking Symbyax

 

 

6. Tardive dyskinesia- Symbyax or coming off of Sym. can cause uncontrollable movements (especially of the face and tongue)

 

 

7. Serotonin syndrome- Symbyax’s use can cause this serious syndrome, and you need to tell your doctor if you experience any hallucinations, over-active reflexes, nausea, vomiting, or racing heart beat

 

 

8. Abnormal bleeding- Symbyax can cause unusual bleeding and bruising, especially when taken with a blood thinner, anti-inflammatory, or even aspirin 

 

 

9. Low Salt Levels- Symbyax’s use can cause hyponatremia, and you need to tell your doctor right away if you feel weak or confused, have problems concentrating, or have constant headaches

 

 

The use of Sym. can cause other serious side effects, and you need to discuss all proper side effects and precautions with your doctor before considering Symbyax.  

 

 

 

Is Zelnorm a Dangerous Drug?

 

 

Zelnorm, a drug known in its generic form as Tegaserod, was used in the United States and Canada for five years.  After being used for thousands of patients, Zelnorms stopped being marketed after evidence revealed they may have been more dangerous than was indicated by initial clinical tests.  If you took Zelnorm at any point while it was being sold, you may wonder what dangers the drug posed.  This guide will explain the uses of Zelnorm, its common side effects, and the dangers that took it off the market in 2007.  You'll also learn how to contact an attorney to help you if you believe Zelnorms may have injured you.

 

 

What is Zelnorm Used For?

 

 

Irritable bowel syndrome can take several forms.  While Tegaserod was used for irritable bowel syndrome, it was not for all types of IBS.  Generally, the only people who took Zelnorms were those who had constipation as their primary IBS symptom.  The drug was not used to treat Crohn's Disease or any kind of IBS or inflammatory bowel disease presenting diarrhea as its primary symptom.

 

 

Zelnorm aided IBS sufferers and people with unexplained constipation to live with significantly less discomfort and bloating.  It helps fecal matter move through the gastrointestinal tract, stimulating the reflexes that lead to bowel movements.  This helped to reduce straining and pain during bowel movements for those taking Zelnorms.

 

 

What Are the Side Effects of Zelnorm?

 

 

Zelnorms have a wide variety of side effects that users should be aware of.  The most common side effects associated with the drug include insomnia, diarrhea, headache, nausea, vomiting, joint pain, leg pain, back pain, and nasal congestion.  While these side effects may seem like they are just nuisances, there are also several more serious side effects of Zelnorm.

 

 

Allergic reactions to Zelnorms are rare but have been reported.  Patients experiencing any symptoms of an anaphylactic response including a rash, difficulty breathing, or swelling of the face or throat, may be experiencing a severe and potentially life-threatening allergic reaction.  It is important not to take Zelnorms if you have a history of allergic reactions to it or any related medications.

 

 

IBS patients who take Zelnorm to control their symptoms may be dismayed to learn that patients taking this drug required abdominal surgery, including gallbladder surgery, significantly more often than those who did not take it.  In some instances, Zelnorms can also cause an IBS sufferer to develop colitis, which leads to rectal bleeding and diarrhea.

 

 

How Serious are Reported Side Effects of Zelnorm?

 

 

While these other side effects can be quite severe for IBS sufferers, these were still not the effects that took Zelnorms off the market permanently.  Instead, new evidence showed that people who used Zelnorm were up to 10 times more likely to suffer a heart attack or stroke.  The federal Food and Drug Administration rapidly acted to stop the medication from being sold in 2007.  Canada and India quickly followed in banning the drug from pharmacy shelves.  For a brief time in 2007 and 2008, patients could still obtain Zelnorms through a special program, but this was discontinued after less than a year.

 

 

Have You Been Injured by Zelnorm?

 

 

If you have suffered from severe side effects after taking Tegaserod, you may want to consider talking to an attorney.  Dangerous drugs attorneys can make sure that you are fairly compensated for any side affects you experienced.  If you or a loved one suffered a stroke or heart attack after taking Zelnorms, you may have a case for one of these lawyers.  Often, you can use a lawsuit to get compensation not only for your economic damages (like hospital bills and compensation for missed work), but also for your pain and suffering or loss of quality of life.  Because cardiovascular events are often associated with high levels of suffering and negative impacts on life quality, these lawsuits can sometimes be quite lucrative.

 

 

If you have decided to hire an attorney, you may be overwhelmed by your options.  Web searches don't always reveal the results you want.  If you can't find what you're looking for, consider finding an attorney through a lawyer referral service.  These services are often offered by county and state bar associations, and can give your local options for legal representation.  Usually, placing a call to a lawyer referral service is free and takes just a few minutes.  You'll tell the referral clerk a little about your legal situation, and will then be referred to a lawyer in your area who takes cases like yours.

 

 

Affording a Dangerous Drugs Lawyer

 

 

Many people are scared to pick up the phone and contact a lawyer about the side effects they experienced on Zelnorm, just because they believe they will not be able to afford legal services.  The truth is, if you have been injured after taking Zelnorms, you may be able to hire an attorney even if you have no money to pay a lawyer upfront.  Often, lawyers will take dangerous drugs cases on a contingency fee basis, allowing you to pay a percentage of your settlement or jury verdict rather than a set fee.

 

 

If you sign a contingency fee agreement with your dangerous drugs attorney, you will only pay legal fees if you win.  Depending on where you're located and the complexity of your case, you can generally expect to pay 25 to 40 percent of your winnings to your lawyer.  Typically, most lawyers will charge a higher percentage rate for cases that go to trial than cases that settle out before a lawsuit can be filed.

 

 

Attorneys only accept cases on contingency if they feel they have a good chance of winning the case and collecting money.  The only way to tell if your specific case will qualify for contingency fee representation is to talk to an attorney.  When you schedule your half-hour consultation after being referred by a lawyer referral service, you can talk to your prospective attorney about fee structures and whether you qualify for this type of fee.

 

 

 

 

Is Zoloft a Dangerous Drug?

 

 

More Americans are using sertraline (brand name Zoloft) to treat their depression than ever.  As of 2007, Zolofts were taken by more Americans than any other medication in its class.  If you've been prescribed this drug, you may want to know if it has the potential to be dangerous.  If you've already experienced severe side effects, you may want to know what your legal options are and what your next steps should be.  This guide will explain how Zolofts are used and the side effects, both minor and serious, of this medication.  You'll also learn how to consult with an attorney if you've been hurt by this potentially dangerous drug.

 

 

What is Zoloft Used For?

 

 

Zolofts belong to a category of drugs called selective serotonin reuptake inhibitors.  This is the most common type of antidepressant, and drugs like Prozac and Wellbutrin are related to it.  These drugs help alleviate the symptoms of depression by changing the balance of serotonin in the brain.  Zoloft is commonly used as a substitute for tricyclic antidepressants, which can have extremely severe (and very common) side effects.

 

 

Sertraline is considered more effective than several other antidepressants in its class, and studies have shown that it can also make a positive impact on symptoms of obsessive-compulsive disorder, panic disorder, social phobias, body dysmorphic disorder, and post-traumatic stress disorder (PTSD).  Zolofts can also be used to assist women who have pre-menstrual dysphoric disorder (PMDD), a severe type of PMS that interrupts daily activities.

 

 

What Are the Side Effects of Zoloft?

 

 

Although Zolofts can be superior to other drugs in their class for treating some types of depression, their side effects can range from disconcerting to deadly.  Nearly half of patients who have been prescribed Zoloft experience sexual dysfunction, typically including a loss of sexual interest and (in men) a physical inability to achieve erection.  Orgasm dysfunction is also common, with many men and women having difficulties achieving orgasm after beginning treatment.  In rare cases, orgasm may no longer lead to pleasure and the genitals may feel numb.  These side effects may persist for years after you have stopped taking Zoloft.

 

 

Diarrhea and nausea are also common side effects, as is sweating that is unexplainable due to temperature.  Dry mouth is commonly reported, as is drowsiness, dizziness, and tremors.  Rarely, sertraline causes insomnia as well.  One unusual side effect of Zolofts is called akathisia, which consists of restlessness and inability to refrain from moving.  Unlike sexual side effects, akathisia usually stops very quickly after a patient stops taking Zoloft.

 

 

For pregnant women, taking Zolofts is a particularly dangerous proposition.  Sertraline crosses the placental barrier in the womb, exposing the developing fetus to high amounts of the chemical (up to a third of the mother's exposure).  Using Zolofts in your first trimester of pregnancy may result in birth defects including missing limbs, undeveloped anuses, and problems with the septum, which divides the baby's nostrils.

 

 

How Serious are Reported Side Effects of Zoloft?

 

 

While most side effects of Zoloft are not life-threatening, several major side effects can be deadly if patients and their doctors don't watch out for it.  Like many antidepressants, Zolofts can actually heighten suicidal ideation and increase the likelihood of a suicide attempt.  The reasons for this counterintuitive effect are still being debated, but it is important to talk to your doctor if you experience feelings of hopelessness or feel suicidal after starting to take Zoloft.

 

 

Zoloft is also potentially deadly in two specific circumstances: when patients overdose, and when they stop using the medication suddenly.  Overdoses can lead to a fast, irregular heartbeat, vomiting, and seizures.  Overdosing on this medication can be fatal, so if you believe you have taken too many Zolofts, you should contact your local Poison Control Hotline or go to the emergency room immediately.

 

 

Stopping your medication suddenly can also be very dangerous.  Intense mood swings and vivid nightmares are common when people stop taking Zoloft all at once, and some people report strange headaches or “electrical” feelings in their bodies.  These side effects can be dangerous on their own, but are even more dangerous if they trigger a major depressive episode or suicide attempt.  Anyone attempting to stop taking Zolofts should contact their doctor for a medication protocol that slowly lowers your dosage.

 

 

Have You Been Injured by Zoloft?

 

 

If you or a loved one has been hurt because they took Zolofts (including women whose babies had congenital defects as a result of sertraline use in the first trimester), you should contact a product liability attorney as soon as possible.  Some product liability attorneys specialize in suing companies that manufacture and sell dangerous drugs like Zoloft.  You may be eligible to receive compensation for your economic damages, as well as your pain and suffering and loss of enjoyment of life.

 

 

One of the best ways to find an attorney to take this kind of case in your area is to talk to your local bar association's lawyer referral service.  Often, these services can link you for free to an attorney in your area who can take your case.  You'll tell the referral service what issues you have had and why you need a lawyer, and will be referred to attorneys who specialize in cases like yours.  Usually, this process takes only a few minutes, and can save you time instead of doing long web searches that fail to yield a lot of useful information.

 

 

Initially, you'll schedule a half-hour consultation with the attorney you are referred to.  This consultation is generally free or very low cost, and allows you to get a feel for the lawyer before committing to hiring them for your case.  You can ask any questions you like during this consultation, and even if you don't hire the attorney you speak with, they are obligated to keep your information confidential.  Make sure to bring all documentation relating to your Zoloft prescription, as well as information about your injury, to your initial consultation.

 

 

 

 

Frequently Asked Questions about Zometa

 

 

What is Zometa?

 

 

Zometa is a type of zoledronic acid which doctors prescribe for certain cancer patients who are suffering from high levels of calcium in their bloodstream. It might also be prescribed, in cases of multiple myeloma or types of cancer which spreads to the bones from another part of the body, to treat bone damage. Since Zometa is not a form of chemotherapy, it cannot stop a cancerous tumor from growing. In those instances in which it performs successfully, Zometa increases bone density, in the process slowing the breakdown of bone and the resulting emission of calcium into the bloodstream.

 

 

How is Zometa taken?

 

 

Zometa is administered intravenously, which means that a healthcare professional will have to inject it into a patient’s veins. This process usually lasts at least fifteen minutes, and the particular dosage level is based both on the apparent effectiveness of the drug and the patient’s risks for side-effects, such as the presence of a kidney condition.

 

 

Doctors usually prescribe Zometa sessions once every three or four weeks, and they won’t be sure how the previous treatment went until at least one week afterward, since this is the amount of time needed for the drug to take its full effect. Patients usually take calcium and vitamin D supplements while undergoing Zometa treatment in order to facilitate bone regrowth.

 

 

What are the common side effects of Zometa?

 

 

Most patients suffer only very minor side effects from Zometa. The most common are dizziness, headache and some flu-like symptoms. More serious side-effects include new pains in the patient’s jaw, hip, thigh, or groin, tingling or numbness anywhere in the body, and some visual blurriness or other eye problems. A change in the amount that you urinate might also be a sign of a very serious side effect, something which might result in kidney failure if not treated, so you should consult a doctor right away if you notice a change.

 

 

Are some people allergic to Zometa?

 

 

Yes, some individuals do develop an allergy to Zometa, but this is very rare. Symptoms of an allergic reaction include a rash, itching, severe dizziness, difficulty breathing, and painful itching or swelling, especially if it is in your face, mouth or throat. If you notice these symptoms, contact a medical professional right away.

 

 

Are there any more dangerous side effects of Zometa?

 

 

In recent years, Zometa as well as other bisphosphonates which work similarly such as Actonel, Boniva, Didronel, Fosamax Skelid, Aredia, and Bonefos have been linked to some very serious side effects which could potentially be deadly. Since these side effects haven’t necessarily been advertised, many individuals have taken filed lawsuits against the manufacturers of Zometa.

 

 

If you’ve suffered from one of the following conditions and are taking Zometa, then you should consult an attorney right away:

 

 

• Femur Fractures: Femur fractures occur just below the hip joint and can be extremely painful. The American Society of Bone and Mineral Research found that Zometa and other bisphosphonates should rewrite their warning labels because there is a verifiable connection between these drugs and atypical femur fractures. The study that they conducted involved 310 randomly selected cases of atypical femur fracture, and in 291 of these 310 cases, the patients turned out to be taking Zometa, usually for five years or more. The FDA confirmed the findings of the Society in a report which linked bisphosphonates with atypical femur fractures for individuals who’ve taken the drug for at least four years.

 

 

• Esophageal Cancer: The British Medical Journal linked bisphosphonates to cancer of the esophagus in those cases in which the bisphosphonates were taken for at least five years. The findings were that for such patients aged 60 to 70, the risk for developing cancer was 2 in 1,000 or twice the normal risk for patients aged 60 to 70. Additionally, the FDA has verified at least thirty-four cases of esophageal cancer have been caused by the use of bisphosphonates including Zometa, and an additional thirty-four cases have been found in Europe and Japan.

 

 

• Severe Musculoskeletal Pain: The FDA released a press statement in January 2008 that they were worried that doctors were underestimating the linkage between bisphosphonates and severe pain in the bones, joints, or muscles. Since this pain is sometimes debilitating, it’s a very serious consequence. Although further research is needed into the risk factors for this severe musculoskeletal pain, the FDA assured the public that bisphosphonates are to blame in many cases, and the discontinued use of bisphosphonates can be seen to cause an end to the symptoms.

 

 

• Osteonecrosis of the Jaw: Osteonecrosis of the Jaw is often abbreviated to ONJ or else referred to more colloquially as dead-jaw syndrome. The condition can be defined as failure of the jaw to heal after minor trauma like tooth extraction. This will cause the bone of the jaw to be exposed, which is not only a disfiguring condition but a torturously painful one as well. There is significant research to show that high doses of bisphosphonates can be linked to an increased risk for dead-jaw syndrome when the drugs are taken by cancer patients. If you’re on Zometa and feel one of the symptoms of dead-jaw syndrome, such as jaw pain, gum swelling, loose teeth, fluid draining around the guns, or an increased heaviness in your jaw, then you should report them immediately to your doctor.

 

 

What type of legal help can I get?

 

 

Patients who’ve suffered one of these very serious side effects of Zometa may be able to take legal action against the makers of Zometa. Search for a medical malpractice attorney in your area and set-up a consultation appointment during which you can tell them about the injury done to you by taking the drug Zometa. 

 

 

Any medical malpractice attorney who will take your Zometa lawsuit will work on a contingency plan. This means that they’ll only get paid a percentage of your award or settlement, so that if you don’t get an award or settlement, your attorney won’t be paid either. Contingency plans greatly cut down on the risk you take when seeking legal action.

 

 

 

What is Promethazine?

 

 

Promethazine is a type of antihistamine. Belonging to the phenothiazine family, Promethazine yields anti-motion sickness, anticholinergic and antiemetic effects. Moreover, Promethazine is used as a sedative and in some countries, is prescribed to combat insomnia. Promethazine is available over the counter in Australia, Switzerland and the United Kingdom; it is only procured via prescription in the United States. Common brand names of Promethazine are: Fargan, Granesse, Avomine, Romergan, Promethagan, Phenergan, Prothiazine, Atosil, and Sominex in the United Kingdom. 

Promethazine is effective because it alters the actions of chemicals in the brain. Promethazine also acts as an antihistamine; the drug blocks the naturally-occurring effects of histamine in the body. As a result of these effects, Promethazine is used to combat allergy symptoms, such as runny nose, itching, watery or itchy eyes, hives, itchy skin rashes and sneezing. Moreover, Promethazine also prevents motion sickness and combats nausea and vomiting or soreness following surgical procedures. Promethazine should not be administered to treat symptoms associated with pneumonia, asthma or any other lower respiratory tract infection. 

 

 

Side Effects Associated with Promethazine:

 

 

Common side effects of Promethazine include:

 

 

• Confusion (mostly observed in elderly patients)

 

 

• Chest Pressure/Discomfort (typically observed when patient is already taking medication to treat high blood pressure)

 

 

• Parasethisia (tingling, burning, prickling or numbing sensations)

 

 

• Euphoria (this side effect of Promethazine is extremely rare; it is often observed with high doses or in co-administration with CNS depressants/opioids 

 

 

• Constipation

 

 

• Respiratory depression (often observed in patients under the age of 2 and for those patients with severely compromised pulmonary functions)

 

 

• Fatigue, vertigo (rare), drowsiness and dizziness

 

 

• Dry mouth

 

 

• Irritability/Short Temper

 

 

• Extreme side effects of Promethazine include: Neuroleptic malignant syndrome and seizures 

 

 

Because of Promethazine’s potential for more severe side effects, the drug is placed on the list to avoid for elderly patients. In several countries, Promethazine is contra-indicated in patients who are under the age of 2 years old. Promethazine is not recommended for children between the ages of 2 and 6 because of its propensity to cause sleep apnea and respiratory depression. 

 

 

You must immediately stop using Promethazine—and contact your doctor—if you experience twitching or uncontrollable movement of your tongue, face, lips, arms, legs or eyes. These symptoms could be early signs of severe side effects. Promethazine should never be administered to children under the age of 2 years old. Patients taking Promethazine must avoid drinking alcohol; the combination of Promethazine and alcohol can increase some of the above side effects. If you are taking any other medication with Promethazine you must tell your doctor. This includes minerals, vitamins, herbal products and any drug prescribed by another doctor. 

 

 

Before taking Promethazine, you must inform your doctor regarding the presence of any of the following medical conditions:

 

 

• History of seizures

 

 

• Glaucoma 

 

 

• Adrenal Gland Tumor

 

 

• Enlarged prostate or difficult urinating

 

 

• Low levels of calcium in your blood

 

 

• Bone marrow depression

 

 

• Sleep Apnea

 

 

• Severe asthma, chronic obstructive pulmonary disease or other types of breathing problems

 

 

• Kidney or liver disease

 

 

• Stomach ulcers or digestive obstructions

 

 

If you have a history of any of the above conditions you must inform your doctor to undertake a dose adjustment of Promethazine.

 

 

The effects of Promethazine on unborn babies are currently unknown. Regardless, you must inform your doctor if you are pregnant or plan to become pregnant during the administration of Promethazine. 

 

 

How do I take Promethazine?

 

 

You must take Promethazine exactly how it is prescribed by your doctor. Never waver from your doctor’s prescription; do not take Promethazine in larger amounts or for extended periods of time. You must follow the directions on the prescription. Promethazine may be taken with or without food. You should store Promethazine at room temperature and away from heat, light and moisture. 

 

 

What to Avoid when taking Promethazine?

 

 

Promethazine may cause severe side effects that can ultimately impair your reactions or thinking. Please be careful when driving or doing anything that requires you to be alert. Avoid getting up too quickly from sitting or lying positions. Also, avoid drinking alcohol and extended exposure to sunlight or tanning beds when on Promethazine. You should tell your doctor if you are using any of the following drugs/medicines when on Promethazine:

 

 

• Lithium

 

 

• Any type of blood pressure medication such as guanethidine, propranolol, guanethidine etc.

 

 

• Blood thinners

 

 

• Urinary or bladder medications, such as oxybutynin, solifenacin, etc. 

 

 

• Any medicine used to combat Parkinson’s diseases, including pituitary gland tumors, restless leg syndrome etc. 

 

 

• Any medicine administered to treat irritable bowel syndrome or stomach ulcers

 

 

These are just a few examples of medicines that can counteract or negatively affect the administration of Promethazine. To be safe, you should tell your doctor about all of your over-the-counter and prescription medications, minerals, herbal products, vitamins and any other drugs prescribed by other doctors. It is strongly advised that you do not start new medications without informing your doctor. 

 

 

Legal Issues Associated with Promethazine:

 

 

In 2009, the United States Supreme Court ruled on a product liability case involving Promethazine. The case revolved around Diana Levine, a woman suffering from migraine headaches, who was administered Promethazine via an IV. Promethazine was injected improperly resulting in gangrene. Because of the faulty administration—and the subsequent gangrene—Levine’s right forearm was amputated. A state jury awarded Mrs. Levine $6 million in punitive damages. 

 

 

Levine’s case was appealed to the United Supreme Court on the grounds of substantive due process and federal preemption. The United States Supreme Court upheld the original ruling rendered by the state court, stating that the drug’s manufacturer (Wyeth Corporation) could have added a stronger warning concerning the IV administration without violating federal law. In essence, the United States Supreme Court ruling means that the drug manufacturers can be held liable for injuries or the development of medical conditions if warnings regarding potential adverse effects are deemed inefficient by the lower courts. 

 

 

On September 9th of 2009, the United States Food and Drug Administration rendered a decision that a black box warning for injection of Promethazine must be placed on the drug’s packaging. The warning must state the contraindication for subcutaneous application or administration. Additionally, the warning must state that the preferred method of administration for Promethazine is intramuscular; this form of administration reduces the risk of tissue and surrounding muscle damage. 

 

 

 

What is Prozac?

 

 

Prozac (Fluoxetine) is a drug used to treat depression, panic attacks, obsessive-compulsive disorder (perpetual bothersome thoughts that are only cured through the performance of certain actions over and over) and some eating disorders. Prozac is used to alleviate the symptoms of premenstrual dysphoric disorders, including irritability, bloating, mood swings and tenderness of the breasts. Prozac is in a class of drugs/medications called selective serotonin reuptake inhibitors. Prozac is effective because it increases the amount of serotonin, which is a natural substance of the brain that helps maintain mental balance.

 

 

How Should Prozac be used? 

 

 

Prozac is administered as a tablet, a capsule, as a timed-release pill or as a liquid to be consumed via oral administration. Prozac may be taken with or without food. Prozac is typically taken once a day in the morning or twice a day (in the morning and at noon). The timed-release version of Prozac should only be taken once a week. If you are prescribed Prozac, you should take it around the same time every day. Please follow the directions on the prescription label and ask your doctor to explain any parts of the process that you are confused about. Never take more or less of the drug than what is prescribed by your doctor. 

 

 

It often takes 4 to 6 weeks to feel the full effects of Prozac. Regardless of how you feel, you should continue to take Prozac so long as your doctor recommends it. Never stop administration without first consulting with your doctor. If you suddenly stop taking Prozac you may experience severe withdrawal symptoms, including irritability, agitation, dizziness, numbness of the hands or feet, anxiety, confusion, tiredness, difficulty falling asleep, difficult staying asleep, sudden mood changes, agitation, tingling or numbness in the feet or hands, confusion, headaches, tiredness and anxiety. 

 

 

Before Taking Prozac Please Observe the Following Precautions:

 

 

Before taking Prozac:

 

 

• Inform your doctor if you are allergic to any medications

 

 

• Notify your doctor if you are taking Orap, monoamine oxidase or thioridazine or other inhibitors such as Marplan, Nardil, Eldepryl, Zelapar and Parnate. If you are taking any of these drugs or have just recently stopped taking them, your doctor will probably inform you that you should not take Prozac. If you stop taking Prozac, it is strongly recommended that you wait at least five weeks before taking monoamine oxidase inhibitors.

 

 

• Notify your doctor if you are taking any other prescription or nonprescription medication and/or vitamin. Mention anything and everything you are taking.

 

 

• Inform your doctor as to any supplements and/or herbal products you are taking, especially products that contain tryptophan or St. john’s wort. 

 

 

• Tell your doctor if you are pregnant or planning on becoming pregnant. Prozac may impose problems in newborns following delivery if the drug is taken during the latter stages of the pregnancy. 

 

 

• Talk to your doctor regarding the benefits and risks of Prozac; you should have this conversation daily if you are over the age of 65. Older patients should not take Prozac on a daily basis because it is not safe to be used with other medications that are administered for similar treatment purposes. 

 

 

• Understand that Prozac will make you drowsy. Never operate a car or heavy machinery without understanding how Prozac affects you. Remember that consuming alcohol will add to the drowsiness caused by Prozac. 

 

 

Side Effects Caused by Prozac:

 

 

Prozac may cause side effects; please tell your doctor if any of these symptoms are persistent or severe:

 

 

• Nausea

 

• Drowsiness

 

 

• Weakness

 

• Sore Throat

 

• Dry Mouth

 

• Uncontrollable shaking of the body

 

• Weakened appetite

 

• Excessive Sweating

 

• Changes in sex drive

 

• Weight Loss

 

 

Aside from these side effects, Prozac may yield more severe side effects. If you experience any of the following symptoms, please contact your doctor immediately:

 

• Hives

 

• Fever

 

• Joint Pain

 

• Rash

 

• Difficulty swallowing or breathing

 

• Swelling of the throat, tongue, lips, hands, feet, eyes, ankles, lower legs or hands

 

• Confusion, sweating, irregular heartbeat and/or severe muscle stiffness

 

• Seizures

 

• Hearing voices or seeing things that do not exist (hallucinations) 

 

 

In addition to the symptoms mentioned above, Prozac may cause other side effects. In general, if your experience any irregular bodily functions or feelings, please contact your doctor. If you experience serious side effects, you or your medical professional may file reports with the United States Food and Drug Administration. To file reports, please visit the MedWatch Adverse Event Program online or via telephone at 1-800-332-1088.

 

 

In case of an overdose or other medical emergency, please contact your local poison control center at 1-800-222-1222. If you come across a victim of an overdose who is not breathing, please call emergency services at 911. Typical signs of a Prozac overdose include:

 

 

• Confusion

 

• Nervousness

 

• Unresponsiveness

 

• Fever

 

• Fainting

 

• Rapid or pounding heartbeat

 

• Uncontrollable shaking of the body

 

 

Legal Issues and Warnings Associated with Prozac:

 

 

It must be stated that a small number of young adults, teenagers and children (up to 24 years of age) who take antidepressants (such as Prozac) are susceptible to becoming suicidal. In numerous studies it has been revealed that children, teens and young adults who are administered antidepressants to treat mental illness or depression may be more likely to become suicidal than children, teens and young adults who do not take said medication. That being said, experts are still unclear as to how significant the risk is and how much it should be weighed when deciding whether a young person should be placed on antidepressants.   

 

 

Before taking Prozac, please understand that your mental health is susceptible to changing in unexpected ways. You may become suicidal, especially during the beginning stages of your treatment and during any dose fluctuations. If you experience any severe alterations in your mood, you must immediately consult your doctor. Also, understand that your insurance provider will want to observe and meet with you while on Prozac. Be sure to maintain all appointments for visits with your medical representatives and doctors.